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THYROID TRANS ACT - Translation of Thyroid Hormone Actions beyond Classical Concepts (SPP 1629)
Termin:
18.02.2015
Fördergeber:
Deutsche Forschungsgemeinschaft (DFG)
The Senate of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has established a Priority Programme entitled "THYROID TRANS ACT" (SPP 1629). The programme started in 2012 and is designed to run for six years. Applications are now invited for the second three-year period.
The programme focuses on the central question: What defines healthy and diseased thyroid function?
THYROID TRANS ACT deciphers the actions of thyroid hormones (TH) comprising T4 and T3 and novel, endogenous thyroid hormone derivatives such as T2 and thyronamines (from "T4-T0"). In particular, THYROID TRANS ACT investigates (i) classical and non-classical TH and their transporters, (ii) thyronamines and their receptors, and (iii) the interrelatedness of "T4-T0" in target tissues. The programme aims at unravelling consequences of disturbed TH signalling with the goal to prevent and target TH dependent disease.
In the second funding period THYROID TRANS ACT will include projects covering the following topics:
- Networking of TH dependent targets in a cell- and organ-specific context
- Non-classical aspects of TH action
- Relevance of "T4-T0" function in different phases of life
- Linking TH action to disease
- Molecular targeting of TH-related disease
The THYROID TRANS ACT programme will not include projects that focus on
- classical TH action
- pathogenesis of thyroid disorders such as autoimmune disease, goiter, or thyroid tumours
- TH in obesity and oncology
Contact:
Prof. Dr. Dr. med. Dagmar Führer
Klinik für Endokrinologie und Stoffwechselerkrankungen
Universitätsklinikum Essen
ufelandstrasse 55
45122 Essen
phone: +49201723-6401
E-Mail: Dagmar.Fuehrer@uk-essen.de
Prof. Dr. rer. nat. Klaudia Brix
Jacobs University Bremen
Campus Ring 1
28759 Bremen
phone: +49421200-3246
E-Mail: K.Brix@jacobs-university.de
PD Dr. rer. nat. Heike Biebermann
Charité Universitätsmedizin Berlin
Institut für Experimentelle Pädiatrische Endokrinologie
Augustenburger Platz 1
13353 Berlin
phone: +4930450559-828,
E-Mail: Heike.Biebermann@charite.de
Further Information:
http://www.dfg.de/foerderung/info_wissenschaft/info_wissenschaft_14_55/index.html
The programme focuses on the central question: What defines healthy and diseased thyroid function?
THYROID TRANS ACT deciphers the actions of thyroid hormones (TH) comprising T4 and T3 and novel, endogenous thyroid hormone derivatives such as T2 and thyronamines (from "T4-T0"). In particular, THYROID TRANS ACT investigates (i) classical and non-classical TH and their transporters, (ii) thyronamines and their receptors, and (iii) the interrelatedness of "T4-T0" in target tissues. The programme aims at unravelling consequences of disturbed TH signalling with the goal to prevent and target TH dependent disease.
In the second funding period THYROID TRANS ACT will include projects covering the following topics:
- Networking of TH dependent targets in a cell- and organ-specific context
- Non-classical aspects of TH action
- Relevance of "T4-T0" function in different phases of life
- Linking TH action to disease
- Molecular targeting of TH-related disease
The THYROID TRANS ACT programme will not include projects that focus on
- classical TH action
- pathogenesis of thyroid disorders such as autoimmune disease, goiter, or thyroid tumours
- TH in obesity and oncology
Contact:
Prof. Dr. Dr. med. Dagmar Führer
Klinik für Endokrinologie und Stoffwechselerkrankungen
Universitätsklinikum Essen
ufelandstrasse 55
45122 Essen
phone: +49201723-6401
E-Mail: Dagmar.Fuehrer@uk-essen.de
Prof. Dr. rer. nat. Klaudia Brix
Jacobs University Bremen
Campus Ring 1
28759 Bremen
phone: +49421200-3246
E-Mail: K.Brix@jacobs-university.de
PD Dr. rer. nat. Heike Biebermann
Charité Universitätsmedizin Berlin
Institut für Experimentelle Pädiatrische Endokrinologie
Augustenburger Platz 1
13353 Berlin
phone: +4930450559-828,
E-Mail: Heike.Biebermann@charite.de
Further Information:
http://www.dfg.de/foerderung/info_wissenschaft/info_wissenschaft_14_55/index.html