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Characterization of extracellular cold shock protein complexes found in serum
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We have demonstrated that the cold shock proteins Y-box binding protein-1 (YB-1) and its homologue, DNA binding protein A (DbpA), are abundant serum proteins. By ELISA, we observed a linear relationship between both proteins, despite them being secreted independently of one another. This project aims to establish how extracellular cold shock proteins form complexes and to determine their physiological activites.
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Kontakt
PD Dr. Jonathan A. Lindquist
Otto-von-Guericke-Universität Magdeburg
Medizinische Fakultät
Universitätsklinik für Nieren- und Hochdruckkrankheiten, Diabetologie und Endokrinologie
Leipziger Str. 44
39120
Magdeburg
Tel.:+49 391 6724703
Fax:+49 391 6724709
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