Innovationsportal Sachsen-Anhalt

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Pharmakodynamik von Tyrosinkinaseinhibitoren

Finanzierung:
Stiftungen - Sonstige;
This analysis will give a deeper insight into the molecular events required for biological activity of TKIs and will directly translate into clinical application:
(1) In development of appropriate therapeutic TKI dosing schedules,
(2) development of novel chemical compounds that lead to cytoplasmatic retention or accumulation and
(3) a change in the perception of specific biochemical markers to monitor patients for drug response.

Anmerkungen

Schlagworte:
Myeloproliferative Neoplasien, Pharmakodynamik, TKI, TYrosine kinase