« Personen

• Entwicklungsneurobiologie, neuronale Plastizität, Epigenetik, funktionelles Imaging
• Einfluss frühkindlicher emotionaler Erfahrungen/Deprivation/Vernachlässigung auf die Entwicklung von Gehirn und Verhalten, Relevanz für die Entstehung, Prävention und Therapie psychische Erkrankungen
• Zelluläre Mechanismen der erfahrungs- und lerninduzierten synaptischen Plastizität
• Untersuchung pathologischer Effekte von sozio-emotionaler Deprivation auf die funktionelle Hirnreifung: Einfluß der väterlichen Fürsorge, Trennungsstress, Bindungsstörungen

My current research interests include the ontogeny of emotionally modulated juvenile learning events, the development of filial attachment, and the identification of epigenetic factors inducing "abnormal development of behavior and of synaptic connections in limbic brain circuits. We investigates mechanisms of information processing and storage at the cellular and synaptic level in the prefrontal cortex and the limbic system using a variety of methods, including quantitative morphology (light-, confocal- and electron-microscopy), functional imaging (2FDG, SPECT, molecular imaging), in vivo microdialysis and behavioral pharmacology. we have established a variety of animal models to identify the role of perinatal stress, neglect, trauma and emotional deprivation on the development of brain and behavior, in order to understand the impact of early life events on the aetiology of mental disorders. In particular we study the role of paternal care/deprivation on the development of brain and behavior.